Current Research 

We use molecular biology, protein chemistry, cell culture and specialized techniques such as calcium imaging, patch-clamp electrophysiology and advanced microscopy to understand how ion channels work and how they contribute to diseases where they are dysfunctional. We aim to understand the importance of ion channels in maintaining health and balance of organs such as heart, brain, etc. and how their dysfunction may be detrimental for humans. such as in cancer.

 

Currently we are studying the role of T-type calcium channels in breast cancer and their interaction with estrogen receptors.

As an alternate to rodent models, we have Zebrafish animal model in our lab. We are interested in investigating pathological mechanisms using zebrafish animal model. We have established methods for developmental toxicity, cardiotoxicity and neurotoxicity. We have now developed zebrafish xnograft model of zebrafish as well.