Publications
41. Vini D. Meshram, Ramkumar Balaji, Preethi Saravanan, Yashashwini Subbamanda, Waghela Deeksha, Akarsh Bajpai, Himanshu Joshi, Anamika Bhargava, Basant K. Patel. In silico and in vitro studies suggest epigallocatechin gallate (EGCG), a polyphenol in green tea, can bind and modulate the aggregation and cytotoxicity of the full-length TDP-43 protein implicated in TDP-43 proteinopathies. BioRxiv, Pages, 2023.12. 22.573011, https://doi.org/10.1101/2023.12.22.573011.
40. Yashashwini Subbamanda Dinesh, Tharunika Subramanian, Aarushi K Zinzuvadia, Andres D Maturana, Anamika Bhargava*. Divergent outcomes of SAK3, a T-type calcium channel enhancer, in two luminal-A type breast cancer cell lines: T-47D and MCF7. BioRxiv, Pages 2023.11. 16.567333, https://doi.org/10.1101/2023.11.16.567333.
39. M Agarwal, A Sharma, A Kagoo R, A Bhargava*. Interactions between genes altered during cardiotoxicity and neurotoxicity in zebrafish revealed using induced network modules analysis. Scientific Reports 2023 Apr 17;13(1):6257.
38. Pullaguri N, Umale A, Bhargava A*. Neurotoxic mechanisms of triclosan: The antimicrobial agent emerging as a toxicant. J Biochem Mol Toxicol. 2023 Feb;37(2):e23244.
37. Sharma A, Rahman G, Gorelik J, Bhargava A*. Voltage-Gated T-Type Calcium Channel Modulation by Kinases and Phosphatases: The Old Ones, the New Ones, and the Missing Ones. Cells. 2023 Jan 31;12(3):461.
36. Subbamanda YD, Bhargava A*. Intercommunication between Voltage-Gated Calcium Channels and Estrogen Receptor/Estrogen Signaling: Insights into Physiological and Pathological Conditions. Cells. 2022. Nov 30;11(23):3850.
35. Shwetha Sekar, Yashashwini Subbamanda, Narasimha Pullaguri, Ankush Sharma, Chittaranjan Sahu, Rahul Kumar, Anamika Bhargava*. Isoform-specific expression of T-type voltage-gated calcium channels and estrogen receptors in breast cancer reveals specific isoforms that may be potential targets, Current Research in Biotechnology, Volume 4,2022,Pages 459-467,ISSN 2590-2628. https://doi.org/10.1016/j.crbiot.2022.09.009
34. Bhargava, A.*, Pullaguri, N., Bhargava, Y. (2022). Zebrafish as a Xenotransplantation Model for Studying Cancer Biology and Cancer Drug Discovery. In: Bhandari, P.R., Bharani, K.K., Khurana, A. (eds) Zebrafish Model for Biomedical Research. Springer, Singapore. https://doi.org/10.1007/978-981-16-5217-2_3
33. Bhargava A.*, Gorelik J. (2022) Correlating Cardiac Structure to Function Using Nanoscale Resolution Scanning Ion Conductance Microscopy. In: . Bioanalytical Reviews. Springer, Berlin, Heidelberg. https://doi.org/10.1007/11663_2021_10
32. A Kagoo, A Sharma, A Bhargava*. Interactions between genes altered during cardiotoxicity and neurotoxicity in zebrafish revealed using induced network modules analysis. bioRxiv, 2022 - biorxiv.orgBioarxiv
31. New insights into inhibitory nature of triclosan on acetylcholinesterase activity. Narasimha Pullaguri, Andrea R Kagoo, Anamika Bhargava*. Toxicology Volume 466, 30 January 2022, 153080. doi: 10.1016/j.tox.2021.153080.
30. N Pullaguri, A Kagoo, A Bhargava*. Antimicrobial Agent Triclosan Inhibits Acetylcholinesterase Activity in Vitro in a Dose-Dependent Manner. bioRxiv, 2021. doi: https://doi.org/10.1101/2021.06.11.448059
29. Pullaguri, N., Grover, P., Abhishek, S., Rajakumara, E., Bhargava, Y., Bhargava, A*. Triclosan affects motor function in zebrafish larva by inhibiting ache and syn2a genes. Chemosphere. Volume 266, March 2021, 128930. https://doi.org/10.1016/j.chemosphere.2020.128930
28. Neema Kumari, Anamika Bhargava, Subha Narayan Rath. T-type calcium channel antagonist, TTA-A2 exhibits anti-cancer properties in 3D spheroids of A549, a lung adenocarcinoma cell line. Life Sci. 2020 Aug 15;260:118291. doi: 10.1016/j.lfs.2020.118291.
27. Pullaguri N, Nema S, Bhargava Y, Bhargava A*. Triclosan alters adult zebrafish behavior and targets acetylcholinesterase activity and expression. Environ Toxicol Pharmacol. 2020 Apr;75:103311. doi: 10.1016/j.etap.2019.103311.
26.Gaur H, Bhargava A*. Glyphosate induces toxicity and modulates calcium and NO signaling in zebrafish embryos. Biochem Biophys Res Commun. 2019 Jun 11;513(4):1070-1075. doi: 10.1016/j.bbrc.2019.04.074.
25. Bhargava A* and Saha S. T-Type voltage gated calcium channels: a target in breast cancer? Breast Cancer Res Treat. 2018 Sep 21. doi:10.1007/s10549-018-4970-0.
24. Gaur H, Purushothaman S, Pullaguri N, Bhargava Y, Bhargava A*. Sodium benzoate induced developmental defects, oxidative stress and anxiety-like behaviour in zebrafish larva. Biochem Biophys Res Commun. 2018 Jul 20;502(3):364-369.
23. Gaur H, Pullaguri N, Nema S, Purushothaman S, Bhargava Y, Bhargava A*. ZebraPace: An Open-Source Method for Cardiac-Rhythm Estimation in Untethered Zebrafish Larvae. Zebrafish. 2018 Jun;15(3):254-262.
22. Neema Kumari, Himanshu Gaur, Anamika Bhargava*. Cardiac voltage gated calcium channels and their regulation by β-adrenergic signaling. Volume 194, 1 February 2018, Pages 139–149.
21. Bhargava Anamika*, Gorelik J. (2018) Studying Structure and Function of the Heart Cells Using Scanning Ion Conductance Microscopy. In: Kaestner L., Lipp P. (eds) Microscopy of the Heart. Springer, Cham. https://doi.org/10.1007/978-3-319-95304-5_1
20. Schobesberger S, Wright P, Tokar S, Bhargava A, Mansfield C, Glukhov AV, Poulet C, Buzuk A, Monszpart A, Sikkel M, Harding SE, Nikolaev VO, Lyon AR, Gorelik J. T-tubule remodelling disturbs localized β2-adrenergic signalling in rat ventricular myocytes during the progression of heart failure. Cardiovasc Res. 2017 Jun 1;113(7):770-782.
19. Yogesh Bhargava and Anamika Bhargava*. ZebraTrack: An Automated Method to Study Zebrafish Behaviour. LAP LAMBERT Academic Publishing (February 9, 2017). ISBN-10: 3659900516.
18. Alexey V. Glukhov, Anamika Bhargava and Julia Gorelik. Distribution and Regulation of L-type Ca2+ channels in cardiomyocyte microdomains. Microdomains in the cardiovascular system. Cardiac and vascular biology. Springer international publishing. August 2017 ISSN: 2509-7830.
17. Sanchez-Alonso JL*, Bhargava A*, Hara T, Glukhov AV, Schobesberger S, Bhogal N, Sikkel MB, Mansfield C, Korchev YE, Lyon AR, Punjabi PP, Nikolaev VO, Trayanova NA, Gorelik J. Microdomain-Specific Modulation of L-Type Calcium Channels Leads to Triggered Ventricular Arrhythmia in Heart Failure. Circ Res. 2016 Sep 30;119(8):944-55. * equal contribution authors.
16. Nema S, Hasan W, Bhargava A, Bhargava Y. A novel method for automated tracking and quantification of adult zebrafish behaviour during anxiety. J Neurosci Methods. 2016 Sep 15;271:65-75.
15. Miragoli M, Sanchez-Alonso JL, Bhargava A, Wright PT, Sikkel M, Schobesberger S, Diakonov I, Novak P, Castaldi A, Cattaneo P, Lyon AR, Lab MJ, Gorelik J. Microtubule-Dependent Mitochondria Alignment Regulates Calcium Release in Response to Nanomechanical Stimulus in Heart Myocytes. Cell Rep. 2016 Jan 5;14(1):140-51.
14. Glukhov AV, Balycheva M, Sanchez-Alonso JL, Ilkan Z, Alvarez-Laviada A, Bhogal N, Diakonov I, Schobesberger S, Sikkel MB, Bhargava A, Faggian G, Punjabi PP, Houser SR, Gorelik J. Direct Evidence for Microdomain- Specific Localization and Remodeling of Functional L-Type Calcium Channels in Rat and Human Atrial Myocytes. Circulation. 2015 Dec 22;132(25):2372-84.
13. Glukhov AV, Rosenshtraukh LV, Bhargava A, Miragoli M, Boukens BJ. Atrial Fibrillation: Biophysics, Molecular Mechanisms, and Novel Therapies. Editorial. Biomed Res Int. 2015;2015:780671.
12. Verena Burtscher ; Klaus W Schicker; Elena Novikova; Birgit Pöhn; Thomas Stockner; Christof Kugler; Anamika Singh; Christina Zeitz; Marie- Elise Lancelot; Isabelle Audo; Bart Peter Leroy; Michael Freissmuth; Stefan Herzig; Jan Matthes; Alexandra Koschak. Spectrum of Cav1.4 dysfunction in congeital stationary night blindness type 2. Biochim Biophys Acta. 2014 Aug;1838(8):2053-65.
11. Hong T, Yang H, Zhang SS, Cho HC, Kalashnikova M, Sun B, Zhang H, Bhargava A, Grabe M, Olgin J, Gorelik J, Marbán E, Jan LY, Shaw RM. Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia. Nat Med. 2014 Jun;20(6):624-32.
10. Wright PT, Nikolaev VO, O'Hara T, Diakonov I, Bhargava A, Tokar S, Schobesberger S, Shevchuk AI, Sikkel MB, Wilkinson R, Trayanova NA, Lyon AR, Harding SE, Gorelik J. Caveolin-3 regulates compartmentation of cardiomyocyte beta2-adrenergic receptor-mediated cAMP signalling. J Mol Cell Cardiol. 2014 Feb; 67:38-48.
9. Anamika Bhargava*, Xianming Lin, Pavel Novak, Kinneri Mehta, Yuri Korchev, Mario Delmar and Julia Gorelik. Super-resolution scanning patch- clamp reveals clustering of functional ion channels in the adult ventricular myocyte. Circ Res. 2013 Apr 12; 112(8): 1112-20.
8. Lab, MJ, Bhargava A, Wright PT and Gorelik J. The Scanning Ion Conductance Microscope (SICM) for Cellular Physiology. Am J Physiol Heart Circ Physiol. 2013 Jan 1;304(1):H1-11.
7. Bhargava Anamika* and Gorelik Julia. Recording Single-Channel Currents using “Smart Patch-Clamp” Technique. Methods Mol Biol. 2013;998:189-97.
6. Ibrahim M, Siedlecka U, Buyandelger B, Harada M, Rao C, Moshkov A, Bhargava A, Schneider M, Yacoub M, Gorelik J, Knoell R, Terracciano CM. . Telethonin regulates transverse tubule structure and Ca 2+ -induced Ca 2+ release in mouse ventricular myocytes. Hum Mol Genet. 2013 Jan 15;22(2):372-83.
5. Singh Anamika*, Hildebrand ME, Garcia E and Snutch TP. TRPC antagonist SKF 96365 is a potent blocker of T-type calcium channels. Br J Pharmacol. 2010 Jul;160(6):1464-75.
4. Singh Anamika*, Gebhart M, Fritsch R, Sinnegger-Brauns M J, Poggiani C, Hoda J C, Engel J, Romanin C, Striessning J and Koschak A. Modulation of voltage- and Ca2+-dependent gating of CaV1.3 L-type calcium channels by alternative splicing of a C-terminal regulatory domain J Biol Chem. 2008 Jul 25;283(30):20733-44.
3. Singh Anamika*, Hamedinger D, Hoda J C, Gebhart M, Koschak A, Romanin C & Striessning J. C-terminal modulator controls Ca2+-dependent gating of CaV1.4 L-type Ca2+ channels. Nat Neurosci. 2006 Sep;9(9):1108-16
2. Hoda JC, Zaghetto F, Singh Anamika, Koschak A, and Striessnig J: Effects of congenital stationary night blindness type 2 mutations R508Q and L1364H on Cav1.4 L-type calcium channel function and expression. J Neurochem. 2006 Mar;96(6):1648-58.
1. Verma SC, Singh Anamika, Chowdhury SP, Tripathi AK. (2004):Endophytic colonization ability of two deep-water rice endophytes, Pantoea sp. and Ochrobactrum sp. using green fluorescent protein reporter. Biotechnol Lett. 2004 Mar;26(5):425-9.
*First / Corresponding author